This paper reviews an alternative methodological approach to assessment and conseptual foresight of financial sustainability of an enterprise. Any socio-economic system is a complex bio-technical system consisting of: a human - the decision maker, a technical object - machinery, equipment, buildings and structures, and a biological object - animals, plants, soil etc., operating in a consolidated informational field. An important place among the factors shaping financial sustainability of the economic entity is reserved for a human (the decision maker), since a human is a subject that purposefully forces all system's functions to interact. Socio-economic systems are characterized by financial dualism: on the one hand, they generate income, and on the other one, they generate costs. Financial result of a socio-economic system activity is expressed in the difference between revenues and expenditures, and the predominance of revenue over incurred costs speaks about the effectiveness. One of the most important characteristics of financial result is its resistance to various internal and external perturbations. Financial sustainability of the enterprise is reviewed from the perspective of bio-technical approach that includes the HME elements system (human, machine and environment) and allows to determine the contribution of each system element into the final result and the stability of these elements. This approach will allow to improve the adequacy of financial stability assessment results a of company in various states of the economy.

The analysis of functioning of complex production systems in agroindustrial sphere — large crop farms and livestock farms — shows that the basis for dynamic development of their productive activities is based on a reliable and stable operation of the complex biotech (human-machine) systems. Urgent problems, whose solution promotes a dynamic and efficient operation of complex biotechnological systems, are to create mathematical models of the total biotech system, allowing sufficiently informatively guide the work of major agricultural organizations. This paper discusses an alternative methodological approach to assessing and forecasting financial sustainability of an enterprise. An important place among the factors that shape the financial stability of the economic entity, takes the human factor (decision maker). Financial sustainability of the enterprise is seen from the perspective of bio-approach that includes elements of the system MME (man, machine, and environment). This approach improves the results when evaluating the adequacy of the financial stability of companies in various states of the economy. Newly developed approaches and mathematical models to manage systems of biotechnology make it possible to significantly increase the productivity of animals, crop production and the level of socio-economic status of people in the country.