A comprehensive diagnosis of socio-demographic security of the region, which is based on an indicative method of analysis, is presented. In particular, status and dynamics of changes in the socio-demographic security of Sverdlovsk region in the period 2000-2009 is shown, the most problematic areas of life are identified. Priorities and targets in enhancing socio-demographic security of Sverdlovsk region up to 2020 are identified. Among the priority directions, for example, reduction in mortality from external causes of mortality decline in working age, and others worked out forecasts of indicators of population reproduction and probabilistic forecasts population of Sverdlovsk region in 2020 under three scenarios (inertial, and supports efficient) can be identified. Finally, an estimate of projected levels of socio-demographic security of Sverdlovsk region as on 2020 is divided and sorted into blocks.

In the article, the results of the research of correlation of welfare and public health of the population of Russia in the conditions of economic instability are presented. The review of performance indicators of development of public sentiments of society applied both in Russian and foreign practice is submitted. The concept content of the “social and psychological potential of a region” as an indicator of public health of the population is opened. On the basis of this concept, the potential pattern is created. The evaluation method of social and psychological potential of a region is developed, its main idea is an integrated assessment of both the potential of a region in general and its separate components. The assessment of the condition of potential in territorial subjects of the Russian Federation is given. Character and power of correlation between indicators of welfare and level of social and psychological potential of territorial subjects of the Russian Federation on the basis of development of correlation matrixes are revealed, also, the regional consistent patterns and tendencies are determined.

In the article, the approach based on the authors’ hypothesis is considered: the development of Russia has specific characteristics (on the one hand, its size, mentality and certain closed nature of its economy, on the other hand, the considerable dominating resource and human potential, and, as the result, its real role in the world economic community). The diagnostics of these characteristics (at the level of the individual’s welfare and territory of accommodation) reveals crises, estimates threats to region socio-economic development at early stages and helps to evaluate the state of a region for 3-5 years. In other words, managers have time necessary for rapid response to the crisis phenomena and administrative mistakes, for decreasing the impact of the arising threats. The purpose of the article is to present the theoretical and methodological tools of the appearing threats recognition at their early stages, which allows to enter the crisis period with smaller losses. Computational experiments to classify the prior socio-economic crises have been conducted (9 possible options are considered), the trajectories of change of the main indicators of the individual’s welfare and territory of residence influenced by various factors are digitized. On the basis of the proposed approach (named as the economic tomography), the attempt of the comprehensive assessment of the state of Russian typical representative regions is made.